Determining the sequence of building blocks of entire genomes – aka genomics – first came to public attention in the 1990s, with…
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post Eclectic Genomics: Cat Flu, Dolphin Adaptation to Climate Change, Predicting Cancer, and Diagnosing Rare DiseaseRead more
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post A Squishy Sea Creature Regenerates a Body from a Severed HeadRead more
Humans aren’t very good at regeneration — we can do it for skin, bone, and liver, but that’s about it. Flatworms, zebrafish…
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post Experiments Reveal the Early Human Embryo, with Implications for Infertility and Early Pregnancy LossRead more
Several recent reports are filling in the gaps of what we know about the earliest days and weeks of human prenatal development…
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post How Targeted Cancer Drugs Disrupt the Cell CycleRead more
“If you’re an adult with newly diagnosed non-small cell lung cancer that’s spread and tests positive for PDL1 without an abnormal EGFR…
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post How (and Why) the Octopus Edits its RNARead more
What I love most about science in general, and genetics in particular, is when new findings upend everything we thought we knew…
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post Topical Gene Therapy FDA-Approved for Severe Skin Disease, Dystrophic Epidermolysis BullosaRead more
The newest FDA-approved gene therapy treats the severe, skin-peeling condition dystrophic epidermolysis bullosa (DEB). The gene treatment has been a long time coming…
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post Experimental Myotonic Dystrophy Treatment Teams Monoclonal Antibody and siRNARead more
Myotonic dystrophy type 1 (DM1), an inherited disease affecting muscles, was one of the first described “expanding repeat” disorders. In these 50…
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post The Love Songs of W. E. B. Du Bois Celebrates Afro-Indigenous History with Genealogy – No DNA NeededRead more
When a dear friend recommended The Love Songs of W. E. B. Du Bois, I thought the book was a tribute to…
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post Bioprospecting in Dental Tartar from Neanderthals for Novel Antibiotics and Revisiting the Discovery of PenicillinRead more
Dense living communities of hundreds of bacterial species form biofilms on our teeth. Without careful brushing and flossing of this dental plaque…
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post Embracing Diversity, Equity, and Inclusion in Genetics Textbooks and TestingRead more
I just finished revising the fourteenth edition of my college textbook, Human Genetics: Concepts and Applications. The first was published at the…
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post Seventy Years Since Watson and Crick’s Paper Introduced DNA: A Brief History of the Molecule of LifeRead more
On April 25, 1953, “MOLECULAR STRUCTURE OF NUCLEIC ACIDS: A Structure for Deoxyribose Nucleic Acid” was published in Nature. J. D. Watson…
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post Genetic Signature for Drug Addiction Revealed in New Analysis of More Than A Million GenomesRead more
Drug addiction is prevalent and deadly. In the US in 2021, more than 46 million people aged 12 or older had addiction…